Observe Intently (1)istradefylline will raise the amount or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism.fluvoxamine will increase the degree or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.diazepam will boost the amount or impact of tazemetostat by affecting hepatic